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    FSCV Headstage Amplifier Cable Kit

    Part Number
    [FSCV-HS-KIT]

    This FSCV Headstage Amplifier Kit is designed for use with the Pine Research WaveNeuro Fast-Scan Cyclic Voltammetry Potentiostat System and is also compatible with the University of North Carolina UEI Potentiostat System. What makes our headstage amplifier cable kits unique is that each major component is modular. This means they can be swapped out as needed, either to change the gain (i.e., change the amplifier) or because a component was damaged (e.g., animal pulled a wire loose from its solder). In the past, when an issue arose with a headstage cable, which was often a single piece design, you could not use the cable unless you repaired the issue. As a result, many FSCV labs have drawers full of headstage cable components just ready to be sacrificed to get the desired cable back in working condition. The modularity of our headstage cable kits eliminate this problem. Here, you will configure your own headstage cable kit by selecting options for seveal of the components.

    Dagan ChemClamp Compatibility
    The Pine Research FSCV Headstage Amplifier Cable Kits are compatible with the discontinued Dagan ChemClamp, with an additional adapter cable. Select this option below to use this cable kit with your Dagan ChemClamp

    This FSCV Headstage Amplifier Kit is designed for use with the Pine Research WaveNeuro Fast-Scan Cyclic Voltammetry Potentiostat System and is also compatible with the University of North Carolina UEI Potentiostat System. What makes our headstage amplifier cable kits unique is that each major component is modular. This means they can be swapped out as needed, either to change the gain (i.e., change the amplifier) or because a component was damaged (e.g., animal pulled a wire loose from its solder). In the past, when an issue arose with a headstage cable, which was often a single piece design, you could not use the cable unless you repaired the issue. As a result, many FSCV labs have drawers full of headstage cable components just ready to be sacrificed to get the desired cable back in working condition. The modularity of our headstage cable kits eliminate this problem. Here, you will configure your own headstage cable kit by selecting options for seveal of the components.

    Dagan ChemClamp Compatibility
    The Pine Research FSCV Headstage Amplifier Cable Kits are compatible with the discontinued Dagan ChemClamp, with an additional adapter cable. Select this option below to use this cable kit with your Dagan ChemClamp
    Customizable Bundle Product
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    Important
    More Detail
    Specifications
    Working Driven Headstage
    Pine Research currently offers working driven headstage amplifiers. In a working driven system, the reference electrode is grounded. The FSCV potential waveform (ramp) is connected to the non-inverting input of the operational amplifier, while the working electrode is connected to the inverting input. In this arrangement, the voltage at the microelectrode will follow the ramp applied to the inverting input. This means that even when no electrodes are connected (connector just in air) to the headstage amplifier cable, which is connected to the WaveNeuro, HDCV will show a current response that follows the applied waveform, which is the expected behavior for a working driven headstage.

    Pine Research currently offers working driven headstage amplifiers.  In a working driven system, the reference electrode is grounded.  The FSCV potential waveform (ramp) is connected to the non-inverting input of the operational amplifier, while the working electrode is connected to the inverting input.  In this arrangement, the voltage at the microelectrode will follow the ramp applied to the inverting input.1

    In this two-electrode configuration, current arising from electron-transfer reactions, such as the oxidation of dopamine, passes between reference and working electrodes.  The measured current passes through the headstage amplifer, where it is converted to voltage, and sums with the the ramp voltage at the inverting input. Mathematically,

    \displaystyle{V_O=-(i_{in}\times R_F)+V_R}

    where V_O is the output voltage, i_{in} is input current, R_F is feedback resistor (gain), and V_R is the CV ramp voltage.  By rearrangement, the signal voltage (proportional to the current across the 5 MΩ feedback resistor in the 200 nA/V headstage) is then

    \displaystyle{(V_R-V_O)=i_{in}\times R_F=V_{signal}}

    HDCV software, which supports the WaveNeuro FSCV Potentiostat system, performs software subtraction of the ramp according to this relationship, resulting in only the true differential current measurement.1

    1. Takmakov, P.; McKinney, C. J.; Carelli, R. M.; Wightman, R. M. Instrumentation for Fast-Scan Cyclic Voltammetry Combined with Electrophysiology for Behavioral Experiments in Freely Moving Animals. Rev. Sci. Instrum. 2011, 82, 74302.
    FSCV Instrumentation Journal Article
    R.M. Wightman et. al. have well-described FSCV instrumentation, including working driven headstages. Pine Research has based the design of the WaveNeuro FSCV systems and accessories in a similar manner as that which they decribe.
    Product Bundles
    Product bundle
    Bundle includes
    Cables, Headstage amplifier
    Bundle application
    Fast-Scan Cyclic Voltammetry (FSCV)